Blood 1996, 88:2826–2832.įrankel SR: Acute promyelocytic leukemia: new insights into diagnosis and therapy. Raelson JV, Nervi C, Rosenauer A, et al.: The PML/RAR alpha oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells. Haematologica 1999, 84:963–968.ĭegos L, Dombret H, Chomienne C, et al.: All-trans retinoic acid as a differentiation agent in the treatment of acute promyelocytic leukemia. Marasca R, Zucchini P, Galimberti S, et al.: Missense mutations in the PML/RAR alpha ligand binding domain in ATRAresistant As 2O 3 sensitive relapsed acute promyelocytic leukemia. Warrell RP Jr, Frankel SR, Miller WH Jr, et al.: Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans retinoic acid). In vitro studies: structure-function relationship. Cancer Chemother Pharmacol 1997, 40( suppl):S25-S29.Ĭhomienne C, Ballerini P, Balitrand N, et al.: All trans retinoic acid in promyelocytic leukemias. Soignet S, Fleischauer A, Polyak T, et al.: All-trans retinoic acid significantly increases 5-year survival in patients with acute promyelocytic leukemia: long term follow-up of the New York study. Blood 1988, 72:567–576.Ĭastaigne S, Chomienne C, Daniel MT, et al.: All-trans retinoic acid: a differentiation therapy for acute promyelocytic leukemia. Huang M, Yu Chen Y, Shu Rong C, et al.: Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Br J Haematol 1998, 102:1035–1041.įenaux P, Pollet JP, Vanden Bossche L, et al.: Treatment of acute promyelocytic leukemia: a report of 70 cases. Guglielmi C, Martelli MP, Diverio D, et al.: Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome: a cooperative Italian study on 196 cases. Miller WH Jr, Levine K, DeBlasio A, et al.: Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA. N Engl J Med 1993, 329:177–189.īiondi A, Rambaldi A, Pandolfi PP, et al.: Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute polymerase chain reaction. Warrell RP Jr, De The H, Wang Z, Degos L: Acute promyelocytic leukemia.
#Metal clone x rar rar#
Am J Hematol 1980, 8:347–359.ĭe The H, Lavau C, Marchio A, et al.: The PML RAR alpha fusion in RNA generated by the t(15 17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Semin Oncol 1997, 24:92–102.ĭaly PA, Schiffer CA, Wiernik PH: Acute promyelocytic leukemia: clinical management of 15 patients. Leukemia 1994, 8:1264–1268.įenaux P, Chomienne C, Degos L: Acute promyelocytic leukemia: biology and treatment. Pediatr Hematol Oncol 1998, 15:203–206.īiondi A, Rovelli A, Cantu-Rajnoldi A, et al.: Acute promyelocytic leukemia in children: experience of the Italian Pediatric Hematology and Oncology Group (AIEOP). Schaison GS: Acute promyelocytic leukemia in children. It is heavy, melodic and digs down deep to his roots, reminiscent in style of his best selling Shrapnel solo record "Dragon's Kiss."Ġ2.Ebb D, Weinstein H: Diagnosis and treatment of childhood acute myelogenous leukemia.
"LOUDSPEAKER" is exactly the kind of record that Friedman fans have been waiting for. Racking up sales of over 10 million records with Megadeth, Friedman continued to record solo records for Shrapnel, often embarking on musical forays far removed from his work with Megadeth. Marty Friedman began his career as a Shrapnel solo recording artist and later joined forces with guitar virtuoso Jason Becker to form seminal progressive metal pioneers, "Cacophony." Amassing worldwide acclaim as a guitar virtuoso, Marty came to the attention of Megadeth who were looking for a guitarist and the rest is history.
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